Nightshade vegetables, which include tomatoes, potatoes, eggplants, and peppers, have long been discussed in the context of rheumatoid arthritis (RA) due to their natural content of alkaloids, such as solanine. Some proponents suggest that these compounds may trigger inflammation or worsen joint pain in certain individuals with RA. While nightshades are nutritious and contain vitamins, minerals, and antioxidants, anecdotal reports indicate that some people with RA notice increased stiffness, swelling, or discomfort after consuming them.
However, scientific evidence on the impact of nightshades on RA is limited and inconsistent. Most people with rheumatoid arthritis can eat these vegetables without any problems, and eliminating them entirely may unnecessarily restrict important nutrients that support overall health. For those who suspect a sensitivity, a careful elimination and reintroduction trial under the guidance of a healthcare professional or dietitian can help determine whether nightshades influence their symptoms. The key is personalized observation and moderation rather than a blanket avoidance for all RA patients.
