Treatment for celiac plexus pain typically begins with medications aimed at reducing inflammation and interrupting pain signals. These may include nonsteroidal anti-inflammatory drugs,opioids, or neuropathic pain medications. In some cases, complementary approaches like physical therapy, stress-reduction techniques, and dietary modifications may help alleviate symptoms, especially when the pain is linked to underlying gastrointestinal or pancreatic conditions.
For more persistent or severe pain, interventional procedures may be considered. A common option is a celiac plexus block, which involves injecting anesthetic—and sometimes steroid medication—near the plexus to interrupt pain transmission. If successful, this procedure can be repeated as needed. In cases where longer-term relief is needed, a neurolytic block may be used to destroy some of the nerve fibers with alcohol or phenol. These treatments are typically done under imaging guidance and are carefully evaluated for each individual’s needs and
overall health condition.
